Description

(-)-6Beta-Acetylthionormorphine CAS NO 117152-64-4 is a specialized, high-purity chemical compound belonging to the morphinan class. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate or reference standard in the study of opioid receptor activity. It is primarily sought by research institutions, pharmaceutical companies, and analytical laboratories engaged in neuropharmacology, medicinal chemistry, and forensic science. Our supply is characterized by stringent quality control to ensure consistency and reliability for critical applications.

Application

• Pharmaceutical Research Intermediate: Serves as a crucial building block in the synthesis of novel opioid analogs for pharmacological evaluation.
• Reference Standard for Analytical Testing: Used as a certified reference material (CRM) in HPLC, GC-MS, and LC-MS methods for method development, validation, and quality control.
• Neuropharmacology Studies: Employed in in vitro and in vivo research to investigate binding affinity, efficacy, and selectivity at opioid receptor subtypes.
• Medicinal Chemistry Development: Acts as a precursor for structure-activity relationship (SAR) studies aimed at developing new therapeutic agents with modified properties.
• Forensic Analysis and Toxicology: Utilized as an analytical standard for the identification and quantification of related compounds in forensic samples.
• Biochemical Assay Development: Applied in the development of high-throughput screening assays for drug discovery pipelines targeting the central nervous system.

Basic Information

Product Name	(-)-6Beta-Acetylthionormorphine
CAS No.	117152-64-4
Molecular Formula	C19H23NO3S
Molecular Weight	345.46 g/mol
Synonyms	6β-Acetylthionormorphine; (-)-6β-Acetylthionormorphine; 6-Acetyl-6-deoxythionormorphine; 17-Methyl-4,5α-epoxy-7,8-didehydro-6β-thiomorphin-3-ol acetate; Nor-6-acetylthionormorphine; 6β-Acetylthio-7,8-didehydro-4,5α-epoxy-17-methylmorphinan-3-ol
EINECS	Contact for details

Quality Control

Our (-)-6Beta-Acetylthionormorphine is manufactured and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by chromatographic techniques (HPLC). We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific results for identity, assay, and impurity profiles. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.