Description

Hemoglobin Sunnybrook is a well-characterized, recombinant human hemoglobin variant developed for advanced biomedical research and development. This product is critical for studying oxygen transport mechanisms, blood substitute formulations, and the pathophysiology of hemoglobin-related disorders. It serves as an essential reagent for researchers and developers in the pharmaceutical, biotechnology, and diagnostic sectors requiring a consistent and high-purity hemoglobin source.

Application

• Biomedical Research: Fundamental studies on oxygen binding kinetics, allosteric regulation, and protein stability.
• Blood Substitute Development: A key component in the research and formulation of hemoglobin-based oxygen carriers (HBOCs).
• Diagnostic Reagents: Used as a standard or control material in the calibration and validation of clinical analyzers and diagnostic kits.
• Pharmaceutical Testing: Employed in in vitro models to assess drug interactions with blood components and investigate hematological toxicity.
• Biochemical Assays: Serves as a protein standard in electrophoresis, chromatography, and spectroscopic analysis.
• Enzyme & Cell Culture Studies: Provides an oxygen source or a heme-protein model in various enzymatic and cell-based research applications.

Basic Information

Product Name	Hemoglobin Sunnybrook
CAS No.	117056-11-8
Molecular Formula	C2952H4664N812O832S40Fe4
Molecular Weight	~64.5 kDa
Synonyms	Recombinant Human Hemoglobin Sunnybrook; Hb Sunnybrook; rHb Sunnybrook; Hemoglobin variant Sunnybrook; Sunnybrook Hemoglobin; Hb (αV10M); Hemoglobin (αVal10Met); Oxygen-carrying protein Sunnybrook; Methemoglobin Sunnybrook (oxidized form)
EINECS	Contact for details

Quality Control

Our Hemoglobin Sunnybrook is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional characteristics. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere if specified and handled in appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Lyophilized powder, dark red to brown
Identification (IR / HPLC)	Conforms to standard
Purity (HPLC)	≥ 95%
Assay (Hemoglobin Content)	≥ 90% of theoretical
Methemoglobin Content	≤ 5%
Endotoxin	< 1.0 EU/mg
Oxygen Affinity (P50)	Contact for details
Solubility	Clear solution in buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.