Description

Z-Leu-Pro-Oh . Cha CAS NO 116939-86-7 is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of Leucyl-Proline. This compound serves as a crucial high-purity building block in organic synthesis and peptide chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and protease inhibitors.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used as a scaffold or precursor in the development of inhibitors targeting specific proteolytic enzymes.
• Biochemical Tool Compound: Employed in enzymatic studies and biochemical assays to investigate peptide substrate specificity.
• Custom Peptide Synthesis: Essential building block for contract research organizations (CROs) and CDMOs producing custom peptides for clients.
• Academic Research: Used in university and institutional labs for studying peptide structure-activity relationships and synthetic methodology.

Basic Information

Product Name	Z-Leu-Pro-Oh . Cha
CAS No.	116939-86-7
Molecular Formula	C₂₀H₂₈N₂O₅
Molecular Weight	376.45 g/mol
Synonyms	Z-Leu-Pro-OH; CBZ-Leucyl-Proline; N-Carbobenzoxy-L-leucyl-L-proline; (S)-1-((S)-2-(((Benzyloxy)carbonyl)amino)-4-methylpentanoyl)pyrrolidine-2-carboxylic acid; Benzyl N-[(2S)-1-[(2S)-2-carboxypyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]carbamate; Z-L-Leu-L-Pro-OH; Nα-Cbz-L-leucyl-L-proline; N-Cbz-Leu-Pro-OH
EINECS	Contact for details

Quality Control

Our Z-Leu-Pro-Oh . Cha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.