Description

Propanamide, 2-(Dimethylamino)-n-Methyl-, (R)- (9Ci) CAS NO 116882-83-8 is a chiral, high-purity intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which make it a critical building block for creating complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require precise chiral precursors for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for efficacy and environmental safety.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective chemical transformations.
• Fine Chemical Production: Employed in the synthesis of complex specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including new route development and process optimization for chiral molecules.

Basic Information

Item	Detail
Product Name	Propanamide, 2-(Dimethylamino)-n-Methyl-, (R)- (9Ci)
CAS No.	116882-83-8
Molecular Formula	C7H16N2O
Molecular Weight	144.22 g/mol
Synonyms	(R)-2-(Dimethylamino)-N-methylpropanamide; (R)-N-Methyl-2-(dimethylamino)propanamide; (R)-DMAMP; (2R)-2-(Dimethylamino)-N-methylpropanamide; Dexmethylphenidate related compound; Methylphenidate impurity; (R)-N-Methyl-2-(N,N-dimethylamino)propionamide
EINECS	Contact for details

Quality Control

Our production of Propanamide, 2-(Dimethylamino)-n-Methyl-, (R)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including chiral HPLC and NMR, to verify identity, assay, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.