Description

Cefluprenam CAS NO 116853-25-9 is a synthetic cephalosporin antibiotic belonging to the advanced generation of β-lactam compounds. It is valued for its potent antibacterial activity against a broad spectrum of Gram-positive and Gram-negative pathogens, including resistant strains. This high-purity pharmaceutical intermediate is essential for research institutions and manufacturers developing novel antibiotic formulations and combination therapies.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of advanced cephalosporin antibiotic drugs.
• Antimicrobial Research: Key reference standard in microbiological studies to evaluate efficacy against resistant bacterial strains.
• Veterinary Medicine Development: Used in R&D for creating antibacterial treatments for livestock and companion animals.
• Combination Therapy Studies: Investigated for synergistic effects when combined with other antimicrobial agents.
• Academic & Institutional Research: Serves as a critical reagent in university and government lab studies on antibiotic mechanisms of action.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial antibiotic production.

Basic Information

Product Name	Cefluprenam
CAS No.	116853-25-9
Molecular Formula	C20H21N7O7S2
Molecular Weight	535.55 g/mol
Synonyms	Cefluprenam; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[(E)-1-(2-sulfoethyl)pyrazol-4-yl]methylsulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; FK-037; Cefluprenamum; Cefluprenam (INN); 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[(1E)-1-(2-sulfoethyl)-1H-4-pyrazolyl]methyl]thio]methyl]-8-oxo-, (6R,7R)-
EINECS	Contact for details

Quality Control

Our Cefluprenam is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent controls for related substances and residual solvents. Certificates of Analysis (COA) documenting compliance with in-house specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment and sealed immediately after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.