Description

Propanamide, 2-(Dimethylamino)-3-Hydroxy-, (R)- (9Ci) is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a dimethylamino and a hydroxyl group on a propanamide backbone, makes it a versatile intermediate for constructing complex, biologically active molecules. This compound is particularly valuable for research and development in the pharmaceutical and agrochemical industries, where precise stereochemistry is critical for efficacy and safety. Sourcing this material from a reliable supplier ensures consistent quality and supports innovation in high-value chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance activity and reduce environmental impact.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts for stereoselective chemical transformations.
• Fine Chemical Production: Employed in the multistep synthesis of complex fine chemicals and specialty materials requiring high stereochemical fidelity.
• Bioconjugate Chemistry: The functional groups allow for its use in creating labeled probes or conjugates for biochemical and diagnostic applications.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and medicinal chemistry programs within university and corporate laboratories.

Basic Information

Product Name	Propanamide, 2-(Dimethylamino)-3-Hydroxy-, (R)- (9Ci)
CAS No.	116833-21-7
Molecular Formula	C5H12N2O2
Molecular Weight	132.16 g/mol
Synonyms	(R)-2-(Dimethylamino)-3-hydroxypropanamide; D-2-(Dimethylamino)-3-hydroxypropionamide; (R)-3-Hydroxy-2-(dimethylamino)propanamide; 2-(Dimethylamino)-3-hydroxy-(R)-propanamide; (2R)-2-(Dimethylamino)-3-hydroxypropanamide; (R)-3-Hydroxy-N,N-dimethylalaninamide; (R)-DMHP; 116833-21-7 (CAS)
EINECS	Contact for details

Quality Control

Every batch of Propanamide, 2-(Dimethylamino)-3-Hydroxy-, (R)- (9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles determined by advanced techniques like HPLC and chiral chromatography. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and other critical applications. Specifications and COAs are available for review upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.