Description

Olsalazine-o-Sulfate CAS NO 116430-58-1 is a specialized sulfated derivative of the anti-inflammatory drug olsalazine. This compound is primarily utilized as a key intermediate or reference standard in advanced pharmaceutical research and development. It is essential for scientists and manufacturers working on novel drug delivery systems, prodrug development, and metabolic studies. The product's significance lies in its role in creating more targeted and effective therapeutic agents for inflammatory bowel diseases and related conditions.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anti-inflammatory prodrugs and active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of olsalazine-based medications.
• Metabolic Research: Employed in studies investigating the metabolic pathways, sulfation processes, and bioavailability of salicylate-based drugs.
• Prodrug Development: A key candidate for designing colon-targeted drug delivery systems due to its specific chemical properties.
• Biochemical Research: Utilized in in-vitro and in-vivo studies to understand the mechanism of action and efficacy of sulfated drug metabolites.

Basic Information

Product Name	Olsalazine-o-Sulfate
CAS No.	116430-58-1
Molecular Formula	C14H10N2O8S
Molecular Weight	366.30 g/mol
Synonyms	3,3'-Azobis(6-hydroxybenzoic acid) O,O'-disulfate; Disodium azodisalicylate O-sulfate; Olsalazine disulfate; 5,5'-[(1E)-1,2-Diazenediyl]bis[2-hydroxybenzoic acid] O,O'-disulfate; Azodisalicylic acid O,O'-disulfate; Dipotassium azodisalicylate sulfate; Olsalazine sulfate ester
EINECS	Contact for details

Quality Control

Our Olsalazine-o-Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.