Description

3-(2-Pyridylthio)-2-Hydroxypropylagarose is a specialized affinity chromatography medium designed for the purification of biomolecules. This product matters for its high selectivity and binding capacity, enabling efficient isolation and purification processes critical for research and production. It is primarily needed by biotechnology, pharmaceutical, and academic research laboratories for applications such as protein purification, antibody separation, and enzyme immobilization.

Application

• Affinity Chromatography for Protein Purification: Specifically designed for the selective capture and purification of proteins, enzymes, and antibodies.
• Bioconjugate and Immobilization Support: Serves as a solid-phase matrix for the covalent immobilization of ligands, enzymes, or other biomolecules.
• Research & Development: Used in academic and industrial R&D for studying protein-ligand interactions and developing new purification protocols.
• Downstream Bioprocessing: Integral in pilot-scale and production-scale purification workflows for therapeutic proteins and other biologics.
• Diagnostic Kit Manufacturing: Employed in the production of diagnostic components requiring highly purified biological reagents.

Basic Information

Product Name	3-(2-Pyridylthio)-2-Hydroxypropylagarose
CAS No.	116410-73-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pyridylthio-hydroxypropylagarose; 2-Pyridylthio-2-hydroxypropylagarose; PTHP-Agarose; Activated Thiol-Sepharose analog; 3-(2-Pyridyldithio)-2-hydroxypropylagarose (related); Thiopropylagarose derivative; Affinity chromatography medium 116410-73-2
EINECS	Contact for details

Quality Control

Our 3-(2-Pyridylthio)-2-Hydroxypropylagarose is manufactured under a rigorous quality management system. Each batch undergoes comprehensive testing for key parameters such as ligand density, binding capacity, and matrix stability to ensure consistent performance and reproducibility. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. Do not freeze. The product is supplied as a suspension; ensure the storage container remains sealed to prevent evaporation and microbial contamination.

Specification

Item	Specification
Appearance	White to off-white suspension
Matrix	Cross-linked 4% or 6% Agarose beads
Ligand Density	10 - 30 µmol/mL gel (Contact for specific grade)
Binding Capacity (for IgG)	> 20 mg/mL gel
Particle Size	45 - 165 µm
Storage Buffer	20% Ethanol, PBS, or water
pH Stability	3 - 10 (operational)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.