Description

n-Methoxy-n-Methyl-4-(Trifluoromethyl)Benzamide is a specialized chemical building block, specifically a Weinreb amide derivative, valued for its role in facilitating controlled synthetic transformations. Its primary commercial value lies in its utility as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced materials, and fine chemicals who require reliable, high-purity synthetic intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, especially those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the trifluoromethyl moiety imparts desirable biological activity.
• Material Science Research: Serves as a building block for creating novel organic compounds with specific electronic or optical properties.
• Fine Chemical Manufacturing: Employed in multi-step organic synthesis to introduce the 4-(trifluoromethyl)benzoyl group in a controlled manner via its Weinreb amide functionality.
• Academic & R&D Laboratories: Utilized in method development and exploratory chemistry for creating new carbon-carbon and carbon-heteroatom bonds.

Basic Information

Product Name	n-Methoxy-n-Methyl-4-(Trifluoromethyl)Benzamide
CAS No.	116332-61-7
Molecular Formula	C11H12F3NO2
Molecular Weight	247.21 g/mol
Synonyms	4-(Trifluoromethyl)-N-methoxy-N-methylbenzamide; N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide; N-Methoxy-N-methyl-alpha,alpha,α-trifluoro-p-toluamide; 4-(Trifluoromethyl)benzoic acid N-methoxy-N-methylamide; Weinreb amide of 4-(trifluoromethyl)benzoic acid; N,4-Bis(trifluoromethyl)benzamide (incorrect but sometimes searched); N-Methoxy-N-methyl-p-(trifluoromethyl)benzamide
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methyl-4-(Trifluoromethyl)Benzamide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your internal specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.