Description

4-Fluoro-n-Methoxy-n-Methylbenzamide is a high-purity fluorinated aromatic amide building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and methoxy substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display technologies.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Product Name	4-Fluoro-n-Methoxy-n-Methylbenzamide
CAS No.	116332-54-8
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	4-Fluoro-N-methoxy-N-methylbenzamide; N-Methoxy-N-methyl-4-fluorobenzamide; 4-Fluorobenzoyl-N,O-dimethylhydroxylamine; 4-Fluoro-N-methoxy-N-methyl-benzamide; N-Methoxy-N-methyl-4-fluorobenzamide; 4-Fluorobenzoic acid N-methoxy-N-methylamide; 116332-54-8; N-Methoxy-N-methyl-4-fluorobenzamide (Weinreb amide)
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-n-Methoxy-n-Methylbenzamide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.