Description

5-Bromo-2-(Dicyanomethyl)Pyridine is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a bromine substituent and a reactive dicyanomethyl group, makes it an indispensable precursor for constructing complex heterocyclic systems and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Chemical Biology Probes: Utilized to create tagged molecules and activity-based probes for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	5-Bromo-2-(Dicyanomethyl)Pyridine
CAS No.	116195-86-9
Molecular Formula	C8H4BrN3
Molecular Weight	222.04 g/mol
Synonyms	2-(Dicyanomethyl)-5-bromopyridine; 5-Bromo-2-pyridineacetonitrile, α,α-dicyano-; 5-Bromo-2-(dicyanomethyl)pyridine; (5-Bromopyridin-2-yl)malononitrile; 5-Bromo-2-pyridylmalononitrile; 116195-86-9; 5-Bromo-2-(dicyanomethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-(Dicyanomethyl)Pyridine is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical R&D and production processes. Our standard grade typically meets a purity specification of ≥97% (HPLC), with comprehensive identity confirmation via FT-IR, 1H/13C NMR, and mass spectrometry. Certificates of Analysis (COA) detailing batch-specific results are provided with each shipment. We support development with custom purity grades (e.g., ≥98%, ≥99%) and can align with relevant pharmacopeial or internal quality standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.