Description

(R)-(-)-(2-Methylacryloyl)-2,10-Camphorsultam is a high-purity chiral auxiliary and building block derived from camphorsultam, widely recognized for its utility in asymmetric synthesis. Its core value lies in enabling the production of enantiomerically pure compounds, which is critical for the efficacy and safety of advanced pharmaceuticals and agrochemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral intermediates.

Application

• As a chiral auxiliary in the asymmetric synthesis of active pharmaceutical ingredients (APIs).
• Building block for constructing complex, enantiomerically pure molecules in medicinal chemistry research.
• Key intermediate in the development of agrochemicals, such as herbicides and fungicides, with specific stereochemistry.
• Use in academic and industrial research for methodological studies in asymmetric catalysis and synthesis.
• Precursor for specialty ligands and catalysts used in enantioselective transformations.
• Intermediate in the synthesis of flavors, fragrances, and other fine chemicals where optical purity is paramount.

Basic Information

Product Name	(R)-(-)-(2-Methylacryloyl)-2,10-Camphorsultam
CAS No.	116195-15-4
Molecular Formula	C₁₄H₂₁NO₄S
Molecular Weight	299.39 g/mol
Synonyms	(R)-(-)-2-Methylacryloyl-2,10-camphorsultam; (R)-N-(2-Methyl-1-oxo-2-propen-1-yl)-10,2-camphorsultam; (R)-3-[(2-Methylprop-2-enoyl)amino]-7,7-dimethyl-2-oxo-1-thia-3-azaspiro[4.4]nonane 1,1-dioxide; (R)-N-Methacryloylcamphorsultam; (R)-N-Methacryloyl-10,2-camphorsultam; (R)-(-)-N-Methacryloylcamphorsultam; Evans Chiral Auxiliary Derivative; Camphorsultam Methacrylate Derivative
EINECS	Contact for details

Quality Control

Our (R)-(-)-(2-Methylacryloyl)-2,10-Camphorsultam is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and optical purity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.