Description

Cyclohexanecarboxamide, 2-(Hydroxymethyl)-, (1S-Trans)- (9Ci) is a high-purity chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is critical for producing enantiomerically pure compounds with specific biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key building block for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts and auxiliaries.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Contract Research: A valuable compound for universities and CROs (Contract Research Organizations) conducting research in medicinal chemistry and synthetic methodology.

Basic Information

Product Name	Cyclohexanecarboxamide, 2-(Hydroxymethyl)-, (1S-Trans)- (9Ci)
CAS No.	116174-40-4
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(1S,2R)-2-(Hydroxymethyl)cyclohexanecarboxamide; (1S-trans)-2-(Hydroxymethyl)cyclohexanecarboxamide; trans-2-(Hydroxymethyl)cyclohexanecarboxamide; (1S,2R)-2-Hydroxymethyl-cyclohexanecarboxylic acid amide; 2-(Hydroxymethyl)cyclohexanecarboxamide; Cyclohexanecarboxamide, 2-(hydroxymethyl)-, (1S,2R)-
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarboxamide, 2-(Hydroxymethyl)-, (1S-Trans)- (9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and chiral integrity, which are paramount for sensitive synthetic applications. A detailed Certificate of Analysis (COA) including chiral purity (enantiomeric excess) is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.