Description

Kinase (Phosphorylating), Phosphatidylinositol 3- is a highly specific enzyme critical for catalyzing the phosphorylation of phosphatidylinositol substrates. This compound is essential for fundamental biochemical research, particularly in the study of intracellular signaling pathways related to cell growth, proliferation, and survival. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science research sectors for target validation, drug discovery, and mechanistic studies.

Application

• Biochemical Research & Target Identification: Used as a key reagent to study the PI3K/Akt/mTOR signaling pathway, a crucial regulator in cellular metabolism and cancer biology.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) assays to identify and characterize novel kinase inhibitors for therapeutic development.
• Enzyme Kinetics & Mechanism Studies: Facilitates the investigation of phosphorylation kinetics, substrate specificity, and enzyme inhibition mechanisms.
• Diagnostic Kit Development: Serves as a core component in the development of diagnostic assays for monitoring kinase activity in clinical samples.
• Cell Signaling Pathway Analysis: Essential for in vitro studies to map signal transduction networks and understand disease etiology.
• Academic & Institutional Research: A fundamental tool for universities and research institutes conducting basic science in molecular biology and biochemistry.

Basic Information

Item	Detail
Product Name	Kinase (Phosphorylating), Phosphatidylinositol 3-
CAS No.	115926-52-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PI3 Kinase; Phosphatidylinositol 3-Kinase; PI 3-Kinase; PtdIns 3-Kinase; 1-Phosphatidylinositol 3-Kinase; EC 2.7.1.137; PI3K; Class I PI 3-Kinase
EINECS	Contact for details

Quality Control

Our Kinase (Phosphorylating), Phosphatidylinositol 3- is produced and tested under stringent quality management systems to ensure high purity, specific activity, and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as activity units, purity, and stability. We adhere to relevant guidelines for research-grade biochemicals to support reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Concentration	Provided on COA
Buffer Composition	Provided on COA
Stability	Stable under recommended storage conditions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.