Description

(S)-1-Cbz-Amino-2-Boc-Amino-4-Methylpentane CAS NO 115654-39-2 is a high-purity, protected dipeptide building block essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemistry and orthogonal protecting group strategies in complex molecule assembly. It is primarily utilized in the pharmaceutical industry for the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and novel drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex peptide-based drugs and bioactive molecules.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid derivative for the sequential construction of custom peptides.
• Medicinal Chemistry Research: Serves as a crucial building block for structure-activity relationship (SAR) studies and lead optimization.
• API Development: Integral in the multi-step synthesis of Active Pharmaceutical Ingredients requiring specific (S)-configuration.
• Bioconjugation: Can be employed in the preparation of peptide-protein conjugates or peptide-drug conjugates (PDCs).
• Chemical Biology Probes: Used to create labeled or modified peptides for studying biological processes and interactions.

Basic Information

Product Name	(S)-1-Cbz-Amino-2-Boc-Amino-4-Methylpentane
CAS No.	115654-39-2
Molecular Formula	C20H32N2O4
Molecular Weight	364.48 g/mol
Synonyms	(S)-N-[(Benzyloxy)carbonyl]-N'-(tert-butoxycarbonyl)-L-leucinamide; (S)-N-Cbz-N'-Boc-Leucinamide; (S)-Nα-Cbz-Nε-Boc-L-Lysine Analogue; (S)-1-(Benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)-4-methylpentane; Boc-Leu-Cbz; Z-Leu-Boc; N-Cbz-N'-Boc-L-Leucinamide; (S)-2-((tert-Butoxycarbonyl)amino)-1-(((benzyloxy)carbonyl)amino)-4-methylpentane
EINECS	Contact for details

Quality Control

Our (S)-1-Cbz-Amino-2-Boc-Amino-4-Methylpentane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.