Description

Biotinyl-Angiotensinii CAS NO 115645-39-1 is a biotin-conjugated derivative of the vasoactive peptide Angiotensin II, designed for advanced biochemical research and diagnostic applications. This modification significantly enhances the molecule's utility in detection and isolation techniques, offering superior sensitivity and specificity. It is an essential reagent for researchers and developers in the fields of cardiovascular research, proteomics, and the development of novel immunoassays and biosensors.

Application

• As a high-affinity probe in pull-down assays and streptavidin-biotin interaction studies for protein-protein interaction mapping.
• Critical component in the development and validation of enzyme-linked immunosorbent assays (ELISAs) and other immunoassays targeting the renin-angiotensin system.
• Use as a labeled tracer in receptor binding studies and competitive radioimmunoassays (RIAs) for angiotensin receptor research.
• Facilitates affinity purification and immobilization of angiotensin II-binding proteins or antibodies on streptavidin-coated surfaces.
• Enables sensitive detection and visualization in Western blotting and immunohistochemistry when paired with streptavidin-enzyme or fluorophore conjugates.
• Valuable tool for high-throughput screening (HTS) platforms in pharmaceutical discovery targeting cardiovascular diseases.
• Used in biosensor development for real-time monitoring of angiotensin II pathway activity.
• Serves as a reference standard in analytical method development and quality control for diagnostic kit manufacturing.

Basic Information

Product Name	Biotinyl-Angiotensinii
CAS No.	115645-39-1
Molecular Formula	C58H86N16O12S
Molecular Weight	1191.5 g/mol
Synonyms	Biotin-Angiotensin II; Biotinylated Angiotensin II; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe (Biotinylated); Biotin-Ang II; N-Biotinyl-Angiotensin II; Biotin-LC-Angiotensin II; [Biotinyl]Angiotensin II; Biotin-conjugated Human Angiotensin II
EINECS	Contact for details

Quality Control

Every batch of Biotinyl-Angiotensinii is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency suitable for critical research applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC chromatograms and mass spectrometry data, to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 98% on dried basis
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.