Description

3-(Trifluoromethyl)Pentanoic Acid is a specialized fluorinated carboxylic acid building block valued for its unique combination of lipophilicity and electronic properties imparted by the trifluoromethyl group. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where the introduction of fluorine atoms is critical for modulating biological activity and stability. It serves researchers and process chemists in the pharmaceutical, agrochemical, and advanced material science industries seeking to enhance the performance characteristics of their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine moiety improves lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated as a monomer or modifier to create fluorinated polymers with enhanced chemical resistance, low surface energy, and improved weatherability.
• Ligand & Catalyst Development: Employed in organometallic chemistry to synthesize novel fluorinated ligands for catalytic systems.
• Organic Synthesis Building Block: A versatile reagent for introducing the -CH(CF3)CH2CH2COOH moiety into more complex molecular architectures via esterification, amidation, or reduction reactions.

Basic Information

Product Name	3-(Trifluoromethyl)Pentanoic Acid
CAS No.	115619-30-2
Molecular Formula	C6H9F3O2
Molecular Weight	170.13 g/mol
Synonyms	3-(Trifluoromethyl)valeric Acid; 3-(Trifluoromethyl)pentanoic Acid; Pentanoic acid, 3-(trifluoromethyl)-; β-Trifluoromethylvaleric Acid; 3-TFMVA; 115619-30-2
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Pentanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical properties.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.