Description

(2,3-Dihydro-3-Oxo-4H-Benzo[B][1,4]Oxazin-4-Yl)Acetonitrile, 4-(Cyanomethyl)-3,4-Dihydro-3-Oxo-2H-1,4-Benzoxazine is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a benzoxazinone core and a reactive nitrile group, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and microbial infections.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in display and lighting technologies.
• Ligand and Catalyst Development: The nitrile and carbonyl functionalities allow for coordination chemistry, useful in creating catalysts for asymmetric synthesis.
• Polymer Modification: Can be incorporated into polymer backbones to impart specific thermal, optical, or mechanical properties.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, including cyclization and functional group transformation reactions.

Basic Information

Product Name	(2,3-Dihydro-3-Oxo-4H-Benzo[B][1,4]Oxazin-4-Yl)Acetonitrile, 4-(Cyanomethyl)-3,4-Dihydro-3-Oxo-2H-1,4-Benzoxazine
CAS No.	115615-02-6
Molecular Formula	C11H8N2O2
Molecular Weight	200.20 g/mol
Synonyms	4-(Cyanomethyl)-2H-1,4-benzoxazin-3(4H)-one; 4-(Cyanomethyl)-3,4-dihydro-3-oxo-2H-1,4-benzoxazine; 2H-1,4-Benzoxazin-3(4H)-one, 4-(cyanomethyl)-; 4-(Cyanomethyl)-1,4-benzoxazin-3-one; 115615-02-6; 4-(Cyanomethyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine
EINECS	Contact for details

Quality Control

Our (2,3-Dihydro-3-Oxo-4H-Benzo[B][1,4]Oxazin-4-Yl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.