Description

Hiv (Gp120) Fragment (308-331) CAS NO 115416-08-5 is a synthetic peptide fragment derived from the gp120 envelope glycoprotein of the Human Immunodeficiency Virus (HIV). This specific sequence is critical for research focused on understanding viral entry mechanisms, antigen-antibody interactions, and the development of diagnostic assays and vaccine candidates. It is an essential reagent for biotechnology and pharmaceutical companies, academic research institutions, and diagnostic manufacturers engaged in virology, immunology, and therapeutic discovery.

Application

• Immunological Research: Used as a defined antigen for studying the humoral and cellular immune response to HIV-1.
• Diagnostic Development: Serves as a key component in the development and calibration of ELISA and other immunoassays for HIV antibody detection.
• Vaccine Research: Employed in epitope mapping and as an immunogen in preclinical studies for novel HIV vaccine candidates.
• Structural Biology: Utilized in biophysical studies, such as NMR and X-ray crystallography, to analyze gp120 structure and function.
• Antiviral Drug Screening: Acts as a target in high-throughput screening assays to identify potential entry inhibitors.
• Quality Control: Used as a reference standard for the quality assurance of other HIV-related biological products and reagents.

Basic Information

Product Name	Hiv (Gp120) Fragment (308-331)
CAS No.	115416-08-5
Molecular Formula	C112H185N35O34
Molecular Weight	~2560.9 g/mol
Synonyms	HIV-1 gp120 (308-331) peptide; HIV-1 IIIB gp120 fragment 308-331; gp120 V3 loop region peptide; HIV envelope glycoprotein gp120 fragment; Arg-Ile-His-Ile-Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile-Gly-Lys-Ile-Gly-Asn-Met-Arg-Gln-Ala-His-Cys; RIHRGPGRAFVTIGKIGNMRQAH-C; Peptide from HIV-1 gp120 (strain IIIB)
EINECS	Contact for details

Quality Control

Our Hiv (Gp120) Fragment (308-331) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing purity, amino acid analysis, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ± 10% of theoretical
Net Peptide Content	≥ 70%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.