Description

Antithrombin Iii Glasgow is a specific variant of the serine protease inhibitor Antithrombin III, a key regulator of the blood coagulation cascade. This high-purity biological compound is critical for advanced research and development in hematology and thrombosis. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic institutions focused on hemostasis and anticoagulant therapies.

Application

• Biopharmaceutical Research: Used as a reference standard and active ingredient in the research and development of novel anticoagulant and antithrombotic drugs.
• Diagnostic Reagent Production: Serves as a critical component in the calibration and manufacturing of in-vitro diagnostic (IVD) kits for testing antithrombin III deficiency and related coagulation disorders.
• Biochemical Studies: Essential for in-vitro studies investigating the mechanisms of blood coagulation, serine protease inhibition, and structure-function relationships of antithrombin variants.
• Quality Control Standard: Employed as a purity standard in the quality control laboratories of pharmaceutical companies producing plasma-derived or recombinant antithrombin products.
• Academic & Clinical Research: Supports fundamental and clinical research into thrombophilia, genetic disorders of coagulation, and personalized medicine approaches.

Basic Information

Product Name	Antithrombin Iii Glasgow
CAS No.	115299-92-8
Molecular Formula	Contact for details
Molecular Weight	~58 kDa
Synonyms	ATIII Glasgow; Antithrombin III Glasgow Variant; Serpin C1 Glasgow; AT3 Glasgow; Antithrombin-3 Glasgow; Heparin Cofactor Glasgow; Antithrombin III (Glasgow Mutation)
EINECS	Contact for details

Quality Control

Our Antithrombin Iii Glasgow is produced and handled under strict quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and functional activity. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/SDS-PAGE), functional activity (heparin cofactor assay), and endotoxin levels is provided to guarantee it meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture condensation. Aliquot into working portions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/Activity)	Conforms to standard
Purity (SDS-PAGE)	> 95%
Assay (Functional Activity)	> 90% of stated activity
Protein Content	As per COA
Endotoxin	< 1.0 EU/mg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.