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Gliadin Peptide A (206-217) CAS NO 115288-29-4
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CAS No.:115288-29-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Gliadin Peptide A (206-217) is a defined synthetic peptide fragment corresponding to a specific sequence of the gliadin protein. This high-purity reference standard is critical for research and development in the field of celiac disease and gluten sensitivity. It is primarily utilized by pharmaceutical, diagnostic, and academic research laboratories for epitope mapping, antibody characterization, and the development of novel therapeutic and diagnostic assays.
Application
- Celiac Disease Research: Used as a key antigen for studying immune responses and T-cell epitope mapping related to gluten intolerance.
- Diagnostic Assay Development: Serves as a critical component in the development and calibration of ELISA kits and other immunoassays for detecting anti-gliadin antibodies.
- Therapeutic Vaccine Research: Employed in preclinical studies for the design and testing of potential peptide-based vaccines or tolerizing therapies for celiac disease.
- Biochemical Standard: Acts as a purified reference standard for quality control and method validation in analytical laboratories.
- Antibody Production & Characterization: Used to generate and screen monoclonal or polyclonal antibodies specific to gliadin epitopes.
Basic Information
| Product Name | Gliadin Peptide A (206-217) |
| CAS No. | 115288-29-4 |
| Molecular Formula | C58H89N15O19 |
| Molecular Weight | 1284.4 g/mol |
| Synonyms | α-Gliadin (56-68); Gliadin Peptide A p56-68; Glia-α9; Gluten Peptide; LQLQPFPQPQLPY; H-Lys-Gln-Leu-Gln-Pro-Phe-Pro-Gln-Pro-Gln-Leu-Pro-Tyr-OH; T-cell stimulatory epitope of α-gliadin |
| EINECS | Contact for details |
Quality Control
Our Gliadin Peptide A (206-217) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided to ensure traceability and compliance with research-grade specifications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC & MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Peptide Content | ≥ 70% (by weight) |
| Amino Acid Analysis | Within ±10% of theoretical |
| Solubility | Soluble in water, DMSO, acetic acid |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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