Description

3,4-Difluoroanisole is a versatile fluorinated aromatic ether, a key building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atoms and methoxy group, enabling precise molecular construction for high-performance materials. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a critical intermediate for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the difluoroanisole moiety contributes to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, enhancing electronic properties and thermal stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, lower dielectric constants, and enhance overall material performance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized anisole derivatives into complex molecules.

Basic Information

Product Name	3,4-Difluoroanisole
CAS No.	115144-40-6
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	1,2-Difluoro-4-methoxybenzene; 3,4-Difluorophenyl methyl ether; 4-Methoxy-1,2-difluorobenzene; Anisole, 3,4-difluoro-; 3,4-DFA
EINECS	Contact for details

Quality Control

Our 3,4-Difluoroanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.