Description

Guanidinophenylglycine-2-Naphthylamide is a specialized biochemical reagent featuring a guanidino group linked to a naphthylamide fluorophore. This compound is valued for its role as a selective and sensitive substrate in enzymatic assays, particularly for detecting specific protease activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in biochemical research, drug discovery, and diagnostic development.

Application

• Protease/Enzyme Substrate: Acts as a key fluorogenic substrate for the detection and kinetic study of specific proteolytic enzymes, such as trypsin-like serine proteases.
• Biochemical Research: Used in fundamental research to investigate enzyme mechanisms, inhibition, and protein-protein interactions.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) assays to identify and characterize novel protease inhibitors as potential therapeutic agents.
• Diagnostic Development: Serves as a critical component in the development of fluorometric diagnostic kits for clinical and research applications.
• Cell Biology Studies: Utilized in assays to monitor protease activity within cellular pathways and processes.

Basic Information

Product Name	Guanidinophenylglycine-2-Naphthylamide
CAS No.	115087-92-8
Molecular Formula	C19H19N5O2
Molecular Weight	349.39 g/mol
Synonyms	Guanidinophenylglycine 2-naphthylamide; N-(4-Guanidinophenyl)glycine 2-naphthylamide; 2-Naphthylamide of N-(4-guanidinophenyl)glycine; GPG-2NA; Substrate for trypsin-like proteases; Fluorogenic protease substrate; 4-Guanidinophenylglycine β-naphthylamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade biochemicals. Each batch is characterized to confirm identity, purity, and performance in standard assay conditions. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), spectral data, and functional activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Functional Activity	Conforms to reference standard in assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.