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Biotinyl-ε-Aminohexanoyl-Alanyl-Arginyl-Valyl-Tyrosyl-Isoleucyl-Histidyl-Prolyl-Phenylalanyl(4N3)-Hydroxy CAS NO 115082-72-9
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CAS No.:115082-72-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Biotinyl-ε-Aminohexanoyl-Alanyl-Arginyl-Valyl-Tyrosyl-Isoleucyl-Histidyl-Prolyl-Phenylalanyl(4N3)-Hydroxy is a sophisticated, biotinylated peptide sequence designed for high-affinity molecular recognition and targeting applications. This compound is crucial for advanced research and development in life sciences, offering a powerful tool for conjugation and detection due to the strong avidin-biotin interaction. It is primarily utilized by pharmaceutical R&D teams, diagnostic developers, and academic researchers in biochemistry and molecular biology for applications such as assay development, targeted drug delivery systems, and protein interaction studies.
Application
- Bioconjugation and Probe Development: Used as a key reagent for labeling proteins, antibodies, or other biomolecules with biotin for subsequent detection or purification via streptavidin/avidin systems.
- Diagnostic Assay Components: Serves as a critical component in the development of sensitive ELISA, lateral flow assays, and other immunoassays requiring robust signal amplification.
- Targeted Drug Delivery Research: Investigated in preclinical research for creating biotinylated drug conjugates that can exploit receptor-mediated uptake mechanisms.
- Protein-Protein Interaction Studies: Employed in pull-down assays and affinity chromatography to isolate and study specific protein complexes.
- Cell Surface Labeling and Imaging: Facilitates the fluorescent or enzymatic tagging of specific cell surface receptors for microscopy and flow cytometry analysis.
- Biomaterial Functionalization: Used to modify surfaces (e.g., biosensor chips, nanoparticles) with biotin groups to create versatile platforms for capturing biomolecules.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Biotinyl-ε-Aminohexanoyl-Alanyl-Arginyl-Valyl-Tyrosyl-Isoleucyl-Histidyl-Prolyl-Phenylalanyl(4N3)-Hydroxy |
| CAS No. | 115082-72-9 |
| Molecular Formula | C73H108N20O16S |
| Molecular Weight | 1561.8 g/mol |
| Synonyms | Biotin-Ahx-A-R-V-Y-I-H-P-F(4N3)-OH; Biotinylated Peptide (Ahx-A-R-V-Y-I-H-P-F(4N3)-OH); Biotin-Ahx-ARVYIHPF(4N3)-OH; Biotin-6-Aminohexanoic Acid-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe(4N3)-OH; Biotin-ε-Ahx-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe(4N3)-OH; (4N3)Phe-containing Biotin Peptide; Biotin-Ahx-ARVYIHPF(4-Azido-Phe)-OH |
| EINECS | Contact for details |
Quality Control
Our Biotinyl-ε-Aminohexanoyl-Alanyl-Arginyl-Valyl-Tyrosyl-Isoleucyl-Histidyl-Prolyl-Phenylalanyl(4N3)-Hydroxy is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC & MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Peptide Content | ≥ 80% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Amino Acid Analysis | Within ± 10% of theoretical |
| Water Content (KF) | ≤ 5.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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