Description

Laminin CAS NO 114956-81-9 is a high-purity, biologically active glycoprotein complex that serves as a fundamental component of the basement membrane. This product is essential for researchers and manufacturers requiring a reliable and consistent substrate for cell adhesion, differentiation, and growth studies. It is primarily utilized in advanced life science research, biopharmaceutical development, and tissue engineering applications where precise extracellular matrix (ECM) modeling is critical.

Application

• Cell Culture Substrate: Coating surfaces to promote the attachment, spreading, and proliferation of sensitive cell lines, including primary cells and stem cells.
• Neuroscience Research: Studying neurite outgrowth, axon guidance, and neural regeneration in vitro.
• Cancer Biology: Investigating tumor cell migration, invasion, and metastasis mechanisms related to basement membrane interactions.
• Tissue Engineering & Regenerative Medicine: As a bioactive component in scaffolds designed to mimic native tissue architecture for organoid development and wound healing models.
• Angiogenesis Studies: Supporting the formation of new blood vessels in endothelial cell culture assays.
• Drug Discovery & Toxicity Screening: Providing a physiologically relevant ECM environment for high-content screening and compound efficacy testing.
• Biomaterial Functionalization: Enhancing the biocompatibility and bioactivity of synthetic polymers and medical implants.

Basic Information

Product Name	Laminin
CAS No.	114956-81-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Laminin-1; EHS Laminin; Laminin from Engelbreth-Holm-Swarm murine sarcoma basement membrane; Matrigel Laminin; ECM Glycoprotein; Basement Membrane Glycoprotein; Cell Adhesion Glycoprotein; LAM
EINECS	Contact for details

Quality Control

Our Laminin is produced under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous testing including purity analysis, sterility checks, and functional bioassays to verify performance in cell culture applications. Certificates of Analysis (COA) detailing specific purity, endotoxin levels, and biological activity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive). For long-term storage, aliquot into single-use vials under aseptic conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solution
Identification (SDS-PAGE)	Characteristic band pattern for α, β, and γ chains
Purity (HPLC)	≥ 90%
Protein Content	≥ 95% of total
Biological Activity (Cell Adhesion)	Conforms to reference standard
Endotoxin Level	< 1.0 EU/μg
Sterility	Sterile (where applicable)
Solubility	Soluble in appropriate buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.