Description

4-Bromo-2-Fluorobenzyl Cyanide is a versatile and high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Utilized in exploratory chemistry for developing novel chemical entities and studying structure-activity relationships (SAR).

Basic Information

Product Name	4-Bromo-2-Fluorobenzyl Cyanide
CAS No.	114897-91-5
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	2-Fluoro-4-bromobenzyl cyanide; (4-Bromo-2-fluorophenyl)acetonitrile; 4-Bromo-2-fluorobenzeneacetonitrile; 2-Fluoro-α-(bromomethyl)benzenecarbonitrile; (4-Bromo-2-fluorobenzyl) cyanide; α-(4-Bromo-2-fluorophenyl)acetonitrile; 4-Bromo-2-fluoro-α-tolunitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzyl Cyanide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable, ensuring the material is suitable for demanding applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.