Description

(R)-1-Benzyl-Pyrrolidine-2-Carboxylic Acid Amide is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters because it serves as a crucial building block for the development of novel, optically active pharmaceuticals and fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of novel chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with potentially improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, exploring new synthetic routes and reaction mechanisms.

Basic Information

Product Name	(R)-1-Benzyl-Pyrrolidine-2-Carboxylic Acid Amide
CAS No.	114883-84-0
Molecular Formula	C₁₂H₁₆N₂O
Molecular Weight	204.27 g/mol
Synonyms	(R)-1-Benzyl-2-carbamoylpyrrolidine; (R)-N-(1-Benzylpyrrolidin-2-yl)formamide; (R)-1-Benzyl-2-pyrrolidinecarboxamide; (R)-α-Benzylprolinamide; (2R)-1-Benzyl-2-pyrrolidinecarboxamide; (R)-Prolineamide, 1-benzyl-; (R)-1-Benzylprolinamide
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl-Pyrrolidine-2-Carboxylic Acid Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.