Description

γ-Preprotachykinin Amide (72-92) is a synthetic peptide fragment corresponding to a specific sequence of the preprotachykinin precursor protein. This high-purity peptide is critical for advanced biochemical and pharmacological research, serving as a precise tool for studying neurokinin receptor signaling pathways and related physiological processes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroscience, peptide chemistry, and drug discovery programs.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies investigating the role of tachykinins in the central and peripheral nervous systems.
• Receptor Binding Assays: Employed in competitive binding studies to characterize and quantify neurokinin receptors (NK1, NK2, NK3).
• Biochemical Tool: Serves as a substrate or inhibitor in enzymatic studies related to peptide processing and degradation.
• Pharmaceutical Development: Acts as a key intermediate or reference compound in the discovery and development of novel therapeutics targeting neurokinin pathways.
• Cell Signaling Studies: Applied in vitro to stimulate cellular responses and map signal transduction cascades initiated by tachykinin peptides.
• Antibody Production & Immunoassays: Utilized as an immunogen for generating specific antibodies or as a calibrator in ELISA and other immunoassay formats.

Basic Information

Product Name	γ-Preprotachykinin Amide (72-92)
CAS No.	114882-65-4
Molecular Formula	C115H183N35O32S
Molecular Weight	~2595.0 g/mol
Synonyms	γ-Preprotachykinin (72-92) amide; Tachykinin Precursor 1 (72-92) amide; PPT (72-92) amide; Neurokinin A Precursor Fragment (72-92); H-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2; HKRTDSFVG-LM-NH2 (single-letter); Substance K Precursor (72-92) amide
EINECS	Contact for details

Quality Control

Every batch of γ-Preprotachykinin Amide (72-92) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting standards of research and development. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for purity (HPLC), peptide content, amino acid analysis, and mass spectrometry (MS).

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.