Description

Boc-D-2,4-Dichlorophenylalanine is a high-purity, non-natural amino acid derivative extensively used as a critical chiral building block in advanced organic synthesis. This compound is essential for introducing the unique steric and electronic properties of the D-2,4-dichlorophenylalanine moiety into target molecules under Boc-protection strategies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, protease inhibitors, and other bioactive compounds where precise stereochemistry and side-chain functionality are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide drugs and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the D-2,4-dichlorophenylalanine residue into peptide sequences.
• Protease Inhibitor Development: Serves as a core structural component in the design of inhibitors targeting specific proteases.
• Chemical Biology Research: Employed in the study of protein-protein interactions and enzyme mechanisms using modified peptide probes.
• Agrochemical Research: Potential application as a building block for the synthesis of chiral active ingredients with specific biological activity.
• Material Science: Can be used in the synthesis of specialty polymers and functional materials with tailored properties.

Basic Information

Product Name	Boc-D-2,4-Dichlorophenylalanine
CAS No.	114873-12-0
Molecular Formula	C₁₄H₁₇Cl₂NO₄
Molecular Weight	334.20 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-2,4-dichlorophenylalanine; Boc-D-2,4-Dichloro-Phe-OH; (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(2,4-dichlorophenyl)propanoic acid; tert-Butyloxycarbonyl-D-2,4-dichlorophenylalanine; Boc-D-(2,4-DiCl)Phe; D-2,4-Dichlorophenylalanine N-Boc derivative; N-Boc-D-2,4-dichlorophenylalanine
EINECS	Contact for details

Quality Control

Our Boc-D-2,4-Dichlorophenylalanine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications such as chiral purity, chemical purity (HPLC), and residual solvent content. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.