Description

Boc-D-2,4-Dichlorophenylalanine is a protected, non-natural amino acid derivative essential for advanced peptide synthesis. This compound is a critical chiral building block, enabling the precise construction of complex peptide architectures with enhanced stability and bioactivity. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers developing novel therapeutic peptides, peptidomimetics, and bioactive probes.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Serves as a protected D-amino acid monomer in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methodologies.
• Proteomics Research: Used in the design and production of non-hydrolyzable peptide analogs, enzyme inhibitors, and substrate analogs for biochemical studies.
• Bioconjugation: Acts as a specialty linker or functional handle for creating peptide-drug conjugates or peptide-labeled biomolecules.
• Material Science: Building block for constructing synthetic peptides used in biomaterials and surface functionalization.

Basic Information

Product Name	Boc-D-2,4-Dichlorophenylalanine
CAS No.	114873-04-0
Molecular Formula	C₁₄H₁₇Cl₂NO₄
Molecular Weight	334.20 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-2,4-dichlorophenylalanine; Boc-D-2,4-Dichloro-Phe-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid; D-Boc-2,4-Dichlorophenylalanine; Boc-D-2,4-Cl₂-Phe; tert-Butyloxycarbonyl-D-2,4-dichlorophenylalanine; N-Boc-D-2,4-dichlorophenylalanine
EINECS	Contact for details

Quality Control

Our Boc-D-2,4-Dichlorophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.