Description

Parathyroid-Hormone-Related Protein(1-36), Tyrnh2(36)- CAS NO 114732-67-1 is a synthetic peptide fragment corresponding to the biologically active N-terminal region of parathyroid hormone-related protein (PTHrP). This high-purity peptide is critical for advanced biochemical and pharmacological research, serving as a key reference standard and tool compound. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers focused on calcium metabolism, bone biology, and cancer research.

Application

• Biomedical Research: Used as a precise reference standard in studies of PTHrP signaling pathways, receptor binding assays, and calcium homeostasis.
• Pharmaceutical Development: Serves as a critical tool for screening and validating potential therapeutics targeting PTH/PTHrP receptors for conditions like osteoporosis and hypercalcemia of malignancy.
• Diagnostic Reagent Production: Employed in the development and calibration of immunoassays (ELISA, RIA) for the detection of PTHrP in clinical samples.
• Cell Biology Studies: Applied in vitro to investigate the effects of PTHrP on cell proliferation, differentiation, and apoptosis in bone and cancer cell lines.
• Academic & Institutional Research: A fundamental reagent for universities and research labs exploring endocrinology, skeletal development, and cancer biology.

Basic Information

Product Name	Parathyroid-Hormone-Related Protein(1-36), Tyrnh2(36)- CAS NO 114732-67-1
CAS No.	114732-67-1
Molecular Formula	C181H291N55O51S
Molecular Weight	4108.7 g/mol
Synonyms	PTHrP (1-36), amide; PTHrP (1-36) amide, human; Parathyroid Hormone-Related Protein (1-36) amide; Tyr(36)-PTHrP(1-36)-NH2; PTHrP 1-36 amide (human); PTHLH (1-36), amide; Hypercalcemic factor (1-36); PTH-related peptide fragment 1-36 amide
EINECS	Contact for details

Quality Control

Our Parathyroid-Hormone-Related Protein(1-36), Tyrnh2(36) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.