Description

4,6-Dihydroxypropranolol is a key chemical intermediate and a metabolite of the widely used β-blocker, propranolol. This compound matters for its critical role in pharmaceutical research, particularly in metabolic pathway studies and the development of analytical reference standards. It is primarily needed by pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical research as a reference standard for metabolite identification and quantification.
• Key chemical intermediate in the synthesis of novel β-adrenergic receptor ligands.
• Use in analytical method development and validation for pharmacokinetic studies.
• Biochemical research to study the metabolic pathways and clearance mechanisms of propranolol.
• Production of certified reference materials (CRMs) for quality control laboratories.

Basic Information

Product Name	4,6-Dihydroxypropranolol
CAS No.	114662-06-5
Molecular Formula	C₁₆H₂₃NO₄
Molecular Weight	293.36 g/mol
Synonyms	1-(Isopropylamino)-3-(naphthalen-1-yloxy)propane-2,4-diol; 4,6-Dihydroxypropranolol Hydrochloride (salt form); Propranolol Dihydroxy Metabolite; 4,6-Dihydroxy-1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol; 1-(1-Methylethyl)amino-3-(1-naphthalenyloxy)-2,4-propanediol; 4,6-DiOH-Propranolol; DL-4,6-Dihydroxypropranolol
EINECS	Contact for details

Quality Control

Our 4,6-Dihydroxypropranolol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.