Description

(R)-(+)-Benzyl-3-Acetylaminopyrrolidine is a high-purity, chiral pyrrolidine derivative that serves as a critical building block in advanced organic synthesis. Its enantiomeric purity and functionalized structure make it an indispensable intermediate for the development of novel, biologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly within medicinal chemistry and asymmetric catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) targets.
• Asymmetric Catalysis: Used as a precursor or ligand component in the synthesis of chiral catalysts for enantioselective transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore novel pharmacophores and optimize lead compounds.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology: Utilized in the synthesis of molecular probes and tool compounds for studying biological pathways and enzyme function.
• Academic Research: A valuable reagent for methodological development in organic synthesis and stereochemistry at universities and R&D labs.

Basic Information

Product Name	(R)-(+)-Benzyl-3-Acetylaminopyrrolidine
CAS No.	114636-33-8
Molecular Formula	C₁₄H₂₀N₂O
Molecular Weight	232.32 g/mol
Synonyms	(R)-1-Benzyl-3-(acetylamino)pyrrolidine; (R)-(+)-1-Benzyl-3-acetamidopyrrolidine; (3R)-1-Benzyl-3-(acetylamino)pyrrolidine; (R)-3-Acetamido-1-benzylpyrrolidine; Benzyl (R)-3-acetylaminopyrrolidine; (R)-N-(1-Benzylpyrrolidin-3-yl)acetamide
EINECS	Contact for details

Quality Control

Every batch of (R)-(+)-Benzyl-3-Acetylaminopyrrolidine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess. Our standard pharmaceutical intermediate grade meets rigorous internal specifications, with testing typically including chiral HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.