Description

H-Dap(Boc)-Ome Hcl is a protected amino acid derivative widely utilized as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is primarily used by the pharmaceutical, biotechnology, and research sectors for developing novel therapeutic peptides and conducting biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of the diaminopropionic acid (Dap) residue into peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing peptide fragments in solution.
• Pharmaceutical Research: Serves as a building block for the research and development of peptide-based drug candidates, including antimicrobial peptides and hormone analogs.
• Bioconjugation: The protected amine and carboxylic acid functionalities allow for selective modification and conjugation to other molecules or surfaces.
• Chemical Biology Probes: Used in the synthesis of labeled or modified peptides for studying protein-protein interactions and enzyme activity.
• Academic & Industrial R&D: A standard reagent in laboratories focused on organic synthesis, medicinal chemistry, and peptide science.

Basic Information

Product Name	H-Dap(Boc)-Ome Hcl
CAS No.	114559-25-0
Molecular Formula	C10H20N2O4 • HCl
Molecular Weight	268.74 g/mol (Free base: 232.28)
Synonyms	H-Dap(Boc)-OMe • HCl; (S)-2-((tert-Butoxycarbonyl)amino)-3-aminopropionic acid methyl ester hydrochloride; Methyl (2S)-3-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate hydrochloride; Boc-Dap-OMe • HCl; Boc-L-2,3-diaminopropionic acid methyl ester hydrochloride; Nα-Boc-L-2,3-diaminopropionic acid methyl ester hydrochloride; L-Dap(Boc)-OMe hydrochloride; N-Boc-L-2,3-diaminopropionic acid methyl ester HCl
EINECS	Contact for details

Quality Control

Our H-Dap(Boc)-Ome Hcl is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards and can support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.