Description

(5R,6S)-3-(4-Carbamoylphenoxy)-6β-[(R)-1-Hydroxyethyl]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid Sodium Salt is a high-purity pharmaceutical intermediate and a key derivative in the synthesis of advanced β-lactam antibiotics. This compound is critical for research and development in medicinal chemistry, particularly for creating novel antibacterial agents with targeted activity. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of next-generation carbapenem and penem class antibiotics.
• Antibacterial Research: Used in medicinal chemistry for the research and development of new antibacterial compounds to combat resistant strains.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key precursor in the multi-step synthesis of complex β-lactam APIs.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for antibiotic production in pilot and commercial scales.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Studies: Utilized in studies investigating the mechanism of action and structure-activity relationships (SAR) of β-lactam antibiotics.

Basic Information

Item	Details
Product Name	(5R,6S)-3-(4-Carbamoylphenoxy)-6β-[(R)-1-Hydroxyethyl]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid Sodium Salt
CAS No.	114549-95-0
Molecular Formula	C16H15N2O6SNa
Molecular Weight	386.35 g/mol
Synonyms	Sodium (5R,6S)-3-(4-carbamoylphenoxy)-6-[(1R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate; 4-Carbamoylphenoxy Penem Sodium Salt; Sodium 3-(4-Carbamoylphenoxy)-6-[(1R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate; (5R,6S)-3-(4-Carbamoylphenoxy)-6-[(1R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt; Penem Derivative Sodium Salt; CAS 114549-95-0
EINECS	Contact for details

Quality Control

Our (5R,6S)-3-(4-Carbamoylphenoxy)-6β-[(R)-1-Hydroxyethyl]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid Sodium Salt is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.