Description

β-Preprotachykinin (111-126) CAS NO 114547-33-0 is a synthetic peptide fragment corresponding to a specific sequence of the β-preprotachykinin precursor protein. This compound is of significant value as a high-purity biochemical tool for advanced research in neurobiology and peptide signaling pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in the study of tachykinins, neuropeptides, and related receptor interactions.

Application

• Biochemical Research: Used as a reference standard and analytical tool in studies of tachykinin biosynthesis and processing.
• Neuroscience Studies: Critical for investigating the role of specific preprotachykinin-derived peptides in neuronal communication and function.
• Pharmaceutical Development: Serves as a key intermediate or reference material in the discovery and development of drugs targeting neurokinin receptors.
• In Vitro Assays: Employed in cell-based assays and receptor binding studies to elucidate peptide-receptor interactions and signaling mechanisms.
• Antibody Production: Can be used as an immunogen for generating specific antibodies against the β-preprotachykinin sequence.
• Proteomics & Peptidomics: Acts as a standard in mass spectrometry and chromatographic methods for identifying and quantifying related peptides in complex biological samples.

Basic Information

Product Name	β-Preprotachykinin (111-126)
CAS No.	114547-33-0
Molecular Formula	C78H124N22O22S
Molecular Weight	1761.99 g/mol
Synonyms	β-Preprotachykinin (111-126); Preprotachykinin B (111-126); PPTB (111-126); Tachykinin Precursor 1 Fragment (111-126); Neurokinin A Precursor Peptide (111-126); H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 (Disulfide bridge: Cys3-Cys11); Substance K Precursor (111-126); β-PPT (111-126)
EINECS	Contact for details

Quality Control

Our β-Preprotachykinin (111-126) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with exacting standards for research-grade peptides. Certificates of Analysis (COA) detailing purity, amino acid analysis, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store desiccated at -20°C or below for long-term stability. For short-term use, store at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values (±10%)
Peptide Content	≥ 70%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.