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Fluoromethyl 4-Methylbenzenesulfonate CAS NO 114435-86-8


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CAS No.:114435-86-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Fluoromethyl 4-Methylbenzenesulfonate is a specialized organic sulfonate ester, a key building block in advanced chemical synthesis. This compound is valued for its role as a versatile fluoromethylating agent, enabling the efficient introduction of the fluoromethyl group into target molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A critical reagent for the synthesis of fluoromethyl-substituted active pharmaceutical ingredients (APIs), enhancing metabolic stability and bioavailability.
  • Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides where the fluoromethyl group can improve efficacy and environmental profile.
  • Material Science Research: Employed in the creation of specialty polymers and advanced materials with tailored surface properties.
  • Fluorine Chemistry: Serves as a fundamental building block in organofluorine chemistry for constructing complex molecules in academic and industrial R&D.
  • Radiopharmaceuticals: Potential use as a precursor in the labeling of molecules with fluorine-18 for Positron Emission Tomography (PET) imaging agents.
  • Ligand and Catalyst Development: Utilized for modifying ligands and catalysts to fine-tune their reactivity and selectivity in catalytic processes.

Basic Information

Product Name Fluoromethyl 4-Methylbenzenesulfonate
CAS No. 114435-86-8
Molecular Formula C9H11FO3S
Molecular Weight 218.24 g/mol
Synonyms Fluoromethyl Tosylate; p-Toluenesulfonic Acid Fluoromethyl Ester; 4-Methylbenzenesulfonic Acid Fluoromethyl Ester; Tosyl Fluoromethyl Ester; (Fluoromethyl) 4-Methylbenzenesulfonate; Fluoromethyl Tosylate Ester; Fluoromethyl p-Toluenesulfonate; FMTs
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Quality Control

Our Fluoromethyl 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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