Description

1.6. 2-Methyl-L-Serine Hydrochloride is a non-proteinogenic amino acid derivative, specifically the hydrochloride salt of 2-methyl-L-serine. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, prized for its role in introducing structural complexity and specific stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the 2-methylserine moiety into custom peptides for drug discovery and biochemical research.
• Bioconjugation & Probe Development: Serves as a modified amino acid for creating labeled peptides or protein conjugates used in diagnostic assays and molecular imaging.
• Chemical Biology Research: Employed in studying enzyme mechanisms, protein structure-function relationships, and metabolic pathways.
• Agrochemical Research: Potential intermediate in the synthesis of novel, biologically active compounds for crop protection.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1.6. 2-Methyl-L-Serine Hydrochloride
CAS No.	114396-62-2
Molecular Formula	C4H9NO3 • HCl
Molecular Weight	155.58 g/mol
Synonyms	(2S)-2-Amino-3-hydroxy-2-methylpropanoic acid hydrochloride; L-2-Methylserine hydrochloride; (S)-2-Amino-3-hydroxy-2-methylpropionic acid hydrochloride; 2-Methyl-L-serine HCl; 2-Methylserine hydrochloride; 2-Methyl-L-serine monohydrochloride; (S)-2-Methylserine hydrochloride; 3-Hydroxy-2-methyl-L-alanine hydrochloride
EINECS	Contact for details

Quality Control

Our 1.6. 2-Methyl-L-Serine Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.