Description

2-Amino-3-Iodobenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino and an iodine substituent, makes it a critical precursor for constructing complex heterocycles and functionalized molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and in materials science research.
• Organic Electronic Materials: A potential precursor for the synthesis of functionalized organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create biaryl and other conjugated structures.
• Dye & Pigment Intermediate: Utilized in the synthesis of advanced colorants and functional dyes.

Basic Information

Product Name	2-Amino-3-Iodobenzonitrile
CAS No.	114344-67-1
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	3-Iodo-2-aminobenzonitrile; 2-Amino-3-iodobenzene carbonitrile; Benzonitrile, 2-amino-3-iodo-; 2-Cyano-6-iodoaniline; 6-Iodoanthranilonitrile; 3-Iodoanthranilonitrile; (2-Amino-3-iodophenyl)cyanide
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Iodobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.