Description

(2S,3S)-3-Hydroxy-L-Isovaline CAS NO 114179-07-6 is a non-proteinogenic amino acid derivative characterized by its unique stereochemistry and hydroxylated side chain. This compound is of significant interest in pharmaceutical research and development, particularly as a chiral building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery, peptide mimetics, and metabolic studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and peptidomimetics.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies and enzyme inhibition assays.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships (SAR) and to modulate peptide stability and bioavailability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Nutraceutical & Cosmetic Research: Investigated for potential applications in specialty ingredients due to its unique structural properties.

Basic Information

Product Name	(2S,3S)-3-Hydroxy-L-Isovaline
CAS No.	114179-07-6
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2S,3S)-3-Hydroxyisovaline; L-threo-3-Hydroxyisovaline; (2S,3S)-3-Hydroxy-3-methylbutanoic acid, 2-amino-; 3-Hydroxy-L-isovaline; 2-Amino-3-hydroxy-3-methylbutanoic acid; (2S,3S)-2-Amino-3-hydroxy-3-methylbutyric acid; 3-Hydroxy-3-methyl-DL-norvaline (related to racemic mix); Hylv (possible abbreviation)
EINECS	Contact for details

Quality Control

Our (2S,3S)-3-Hydroxy-L-Isovaline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and specific impurities is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (diastereomeric excess)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.