Description

2,3,6-Trifluorophenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a strategically substituted trifluorophenyl ring, makes it a critical precursor for the development of complex molecules with tailored properties. This high-purity intermediate is primarily sought after by research and development teams and process chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine atoms enhances metabolic stability and bioactivity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the research and development of fluorinated organic semiconductors and charge-transport materials.
• Advanced Material Science: Utilized as a precursor for specialty polymers and functional materials requiring fluorinated aromatic units.
• Custom Synthesis & Contract Research: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	2,3,6-Trifluorophenylacetonitrile
CAS No.	114152-21-5
Molecular Formula	C8H4F3N
Molecular Weight	171.12 g/mol
Synonyms	(2,3,6-Trifluorophenyl)acetonitrile; 2,3,6-Trifluorobenzeneacetonitrile; α-Cyano-2,3,6-trifluorotoluene; 2-(2,3,6-Trifluorophenyl)acetonitrile; 114152-21-5; Trifluorophenylacetonitrile (mixed isomers may be specified); TFPA (abbreviation)
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluorophenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 97.0% (Typical 98.0% - 99.5%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.