Description

Atrial Natriuretic Factor (1-28), Ala(26)- CAS NO 114102-57-7 is a synthetic, biologically active peptide fragment derived from the human atrial natriuretic peptide (ANP) hormone. This high-purity peptide is critical for cardiovascular and renal research, serving as a potent tool for studying natriuresis, diuresis, and vasodilation mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on hypertension, heart failure, and related metabolic disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of the natriuretic peptide system, blood pressure regulation, and renal function.
• Pharmaceutical Development: Serves as a key intermediate or pharmacological tool in the discovery and development of novel cardiovascular therapeutics.
• Diagnostic Assays: Employed in the calibration and validation of immunoassays (e.g., ELISA) designed to measure ANP levels in clinical samples.
• Signal Transduction Studies: Applied in cell-based assays to investigate the activation of guanylyl cyclase receptors (NPR-A) and downstream second messenger pathways.
• Academic & Preclinical Studies: Facilitates in vitro and in vivo research into cardiac physiology, fluid balance, and hormone-receptor interactions.

Basic Information

Product Name	Atrial Natriuretic Factor (1-28), Ala(26)-
CAS No.	114102-57-7
Molecular Formula	C128H204N42O41S2
Molecular Weight	~3081.5 g/mol
Synonyms	ANF (1-28), Ala26-; Atrial Natriuretic Peptide (1-28), Ala(26)-; hANP (1-28), Ala26-; Ala26-ANP (1-28); Atriopeptin (1-28), Ala(26)-; Cardionatrin (1-28), Ala(26)-; Auriculin A (1-28), Ala(26)-
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Factor (1-28), Ala(26)- is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to GMP principles for peptide synthesis, and our quality system is designed to meet the rigorous demands of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Assayed in a suitable cell-based system (Available on request)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.