Description

Proto-Oncogene Mbcl-2 Alpha Protein CAS NO 114100-41-3 is a high-purity, biologically active protein critical for research into cellular apoptosis and cancer biology. This reagent is essential for advancing studies on the Bcl-2 protein family's role in regulating programmed cell death and oncogenesis. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers for target validation, assay development, and biochemical studies.

Application

• Biochemical Research: Used as a standard or reagent in studies investigating the mechanisms of apoptosis and cell survival pathways.
• Drug Discovery & Target Validation: Serves as a key target protein in high-throughput screening (HTS) assays for developing novel oncology therapeutics.
• Diagnostic Development: Employed in the development and calibration of immunoassays and diagnostic kits for cancer research.
• Academic & Pharmaceutical R&D: Essential for fundamental research on protein-protein interactions, signal transduction, and the function of oncogenes.
• Antibody Production & Characterization: Acts as an antigen for generating and testing specific antibodies against the Bcl-2 alpha protein.

Basic Information

Product Name	Proto-Oncogene Mbcl-2 Alpha Protein
CAS No.	114100-41-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	B-cell lymphoma 2 alpha protein; Bcl-2-alpha; Apoptosis regulator Bcl-2 alpha; Bcl-2-like protein 1; BCL2L1; BCL2 alpha isoform; Bcl-2 oncoprotein alpha; Bcl-2-related protein L-1 alpha
EINECS	Contact for details

Quality Control

Our Proto-Oncogene Mbcl-2 Alpha Protein is produced under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC and SDS-PAGE, identity confirmation, and activity assays. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Confirmed by functional assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.