Description

α-L-Lyxopyranoside, Methyl 2,3-Anhydro-4-Deoxy-4-Fluoro- (9Ci) is a specialized fluorinated carbohydrate derivative, serving as a crucial synthetic intermediate in advanced organic and medicinal chemistry. Its unique structure, featuring a fluorine atom at the 4-deoxy position and a 2,3-anhydro bridge, makes it a valuable building block for the development of novel nucleoside analogs and enzyme inhibitors. This high-purity compound is primarily utilized by research institutions and pharmaceutical development companies focused on antiviral, anticancer, and diagnostic probe discovery.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated nucleoside analogs for antiviral and anticancer drug discovery programs.
• Glycobiology Research: Used as a mechanistic probe to study glycosidase enzyme activity and inhibition, leveraging the fluorine atom as a strategic substituent.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize the pharmacokinetic properties of carbohydrate-based therapeutics.
• Diagnostic Agent Development: Potential building block for positron emission tomography (PET) tracer molecules, where fluorine-18 can be introduced.
• Chemical Biology: Employed in the synthesis of activity-based probes (ABPs) to label and study specific carbohydrate-processing enzymes in complex biological systems.
• Academic & Industrial R&D: Fundamental reagent for methodological development in synthetic organic chemistry, particularly in stereoselective glycosylation and fluorination reactions.

Basic Information

Product Name	α-L-Lyxopyranoside, Methyl 2,3-Anhydro-4-Deoxy-4-Fluoro- (9Ci)
CAS No.	114079-43-5
Molecular Formula	C7H11FO4
Molecular Weight	178.16 g/mol
Synonyms	Methyl 2,3-anhydro-4-deoxy-4-fluoro-α-L-lyxopyranoside; 4-Deoxy-4-fluoro-2,3-anhydro-α-L-lyxopyranoside methyl ether; 2,3-Anhydro-4-deoxy-4-fluoro-α-L-lyxopyranoside methyl; Methyl 4-deoxy-4-fluoro-2,3-anhydro-α-L-lyxopyranoside; Fluorinated lyxopyranoside anhydro derivative; 114079-43-5; α-L-Lyxopyranoside, methyl 2,3-anhydro-4-deoxy-4-fluoro-
EINECS	Contact for details

Quality Control

Our α-L-Lyxopyranoside, Methyl 2,3-Anhydro-4-Deoxy-4-Fluoro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our analytical methods, including HPLC, NMR, and MS, are validated to provide reliable specifications for our clients' critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.