Description

Cefaclidine CAS NO 114013-51-3 is a semi-synthetic cephalosporin antibiotic belonging to the third generation of this important pharmaceutical class. It is valued for its broad-spectrum antibacterial activity, particularly against Gram-negative pathogens, and its enhanced stability against β-lactamases. This compound is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of advanced antibiotic formulations for clinical use.

Application

• Active Pharmaceutical Ingredient (API) for injectable antibiotic formulations.
• Pharmaceutical Intermediates in the synthesis of more complex cephalosporin derivatives.
• Biomedical Research for studying bacterial resistance mechanisms and developing new antimicrobial agents.
• Reference Standard in quality control laboratories for HPLC or microbiological assay calibration.
• Veterinary Medicine for developing treatments for bacterial infections in animals.

Basic Information

Product Name	Cefaclidine
CAS No.	114013-51-3
Molecular Formula	C20H21N5O7S2
Molecular Weight	507.54 g/mol
Synonyms	Cefaclidine; Cefaclidin; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7β-[2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylic acid; Antibiotic FR 17027; FR-17027
EINECS	Contact for details

Quality Control

Our Cefaclidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.