Description

n-(4-Iodo-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide is a high-purity, specialized organic intermediate featuring a halogenated pyridine core with a pivalamide substituent. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological disorders or as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated heterocyclic structure.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes due to the reactivity of the iodine moiety.
• Material Science: Potential monomer or additive in the development of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The aryl iodide group makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl systems.

Basic Information

Product Name	n-(4-Iodo-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide
CAS No.	113975-32-9
Molecular Formula	C11H15IN2O
Molecular Weight	318.16 g/mol
Synonyms	4-Iodo-3-pivalamidopyridine; 2,2-Dimethyl-N-(4-iodopyridin-3-yl)propanamide; 3-Pivalamido-4-iodopyridine; N-(4-Iodo-3-pyridinyl)-2,2-dimethylpropanamide; Pivalic acid (4-iodo-3-pyridinyl)amide; 113975-32-9; 4-Iodo-3-pyridinylpivalamide
EINECS	Contact for details

Quality Control

Our n-(4-Iodo-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.