Description

2-Methyl-4-[(4-Trifluoromethyl)Phenyl]-1-Butene CAS NO 113947-86-7 is a specialized organic intermediate featuring a reactive terminal alkene group and a trifluoromethylphenyl moiety. This unique structure makes it a valuable building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where the introduction of fluorine atoms is critical for modulating biological activity and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced material science sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases, where the trifluoromethyl group enhances metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging the fluorine atom's ability to increase lipophilicity and biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorine-containing organic semiconductors and liquid crystal compounds, which are essential for high-performance displays and electronic devices.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing properties such as chemical resistance, thermal stability, and surface characteristics.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions (e.g., Heck, Suzuki) for creating complex, fluorinated biaryl structures.
• Chemical Research & Development: A valuable tool for medicinal and process chemists exploring structure-activity relationships (SAR) and novel synthetic pathways.

Basic Information

Product Name	2-Methyl-4-[(4-Trifluoromethyl)Phenyl]-1-Butene
CAS No.	113947-86-7
Molecular Formula	C12H13F3
Molecular Weight	214.23 g/mol
Synonyms	4-(4-(Trifluoromethyl)phenyl)-2-methyl-1-butene; 2-Methyl-4-[4-(trifluoromethyl)phenyl]but-1-ene; 1-Butene, 2-methyl-4-[4-(trifluoromethyl)phenyl]-; α,γ-Dimethyl-4-(trifluoromethyl)styrene; 4-(4-Trifluoromethylphenyl)-2-methyl-1-butene; 2-Methyl-4-(4-trifluoromethylphenyl)-1-butene
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-4-[(4-Trifluoromethyl)Phenyl]-1-Butene is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as determined by GC, HPLC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.