Description

Hiv (Gp120) Fragment (254-274) CAS NO 113944-46-0 is a synthetic peptide fragment corresponding to a specific region of the HIV-1 envelope glycoprotein gp120. This high-purity biochemical is a critical research tool for studying viral entry mechanisms, antigen-antibody interactions, and for the development of diagnostic assays and vaccine candidates. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on virology and immunology.

Application

• Immunological Research: Used as a specific antigen to study host immune responses, epitope mapping, and antibody characterization against HIV-1.
• Diagnostic Development: Serves as a key component in the development and calibration of ELISA and other immunoassays for HIV detection and research.
• Vaccine Research: Employed in preclinical studies to evaluate the immunogenicity of potential vaccine constructs targeting the gp120 protein.
• Binding Studies: Utilized in surface plasmon resonance (SPR) and other biophysical techniques to analyze interaction kinetics with receptors like CD4 or neutralizing antibodies.
• Cell Biology Studies: Applied in research investigating the molecular details of HIV attachment and fusion with host cells.
• Reference Standard: Acts as a purified standard for quality control and method validation in related bioanalytical workflows.

Basic Information

Product Name	Hiv (Gp120) Fragment (254-274)
CAS No.	113944-46-0
Molecular Formula	C₁₁₀H₁₇₃N₃₅O₃₄
Molecular Weight	2546.8 g/mol
Synonyms	HIV-1 gp120 (254-274) peptide; HIV-1 IIIB gp120 (254-274); gp120 Fragment (254-274); HIV Envelope Glycoprotein gp120 Peptide (254-274); HGP-30 related peptide; AIDS virus gp120 peptide; Synthetic HIV-1 gp120 epitope; Peptide corresponding to residues 254-274 of HIV-1 gp120
EINECS	Contact for details

Quality Control

Every batch of Hiv (Gp120) Fragment (254-274) is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency suitable for research applications. Certificates of Analysis (COA) detailing purity, HPLC chromatograms, and mass spectrometry data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture uptake. For long-term storage, consider under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Molecular Weight (MS)	2546.8 ± 2 Da
Solubility	Soluble in water or dilute aqueous acetic acid
Water Content (K.F.)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.