Description

3-(3-(Trifluoromethyl)Phenoxy)Propan-1-Amine is a high-purity aromatic amine derivative featuring a trifluoromethylphenoxy side chain, offering unique chemical reactivity and stability. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the development of novel active ingredients. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group contributes to lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and alignment agents in display technologies.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for producing specialty polymers with tailored thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and condensation reactions to introduce the phenoxypropylamine moiety into complex molecular architectures.
• Chemical Research & Development: A valuable tool for medicinal chemistry and material science research programs exploring new chemical entities.

Basic Information

Product Name	3-(3-(Trifluoromethyl)Phenoxy)Propan-1-Amine
CAS No.	113896-91-6
Molecular Formula	C10H12F3NO
Molecular Weight	219.20 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenoxy]propan-1-amine; 3-(3-Trifluoromethylphenoxy)propylamine; 1-Amino-3-(3-trifluoromethylphenoxy)propane; γ-(3-Trifluoromethylphenoxy)propylamine; 3-(α,α,α-Trifluoro-m-tolyloxy)propylamine; m-Trifluoromethylphenoxypropylamine; 3-(3-(Trifluoromethyl)phenoxy)propanamine
EINECS	Contact for details

Quality Control

Our 3-(3-(Trifluoromethyl)Phenoxy)Propan-1-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request, supporting compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. Due to its amine functionality, ensure the container is sealed under an inert atmosphere if long-term storage is required to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Refractive Index	1.480 - 1.490
Density	1.25 - 1.35 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.