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Vasopressin, 2-Gly-9-Des-Gly-4-Val-8-Orn- CAS NO 113846-98-3


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CAS No.:113846-98-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Vasopressin, 2-Gly-9-Des-Gly-4-Val-8-Orn- is a synthetic analogue of the neurohypophysial hormone vasopressin, specifically engineered for enhanced research and development applications. This modified peptide is crucial for studying the structure-activity relationships of vasopressin receptors and developing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology, cardiovascular research, and central nervous system disorders.

Application

  • Pharmacological Research: As a key reference standard and tool compound for investigating vasopressin receptor (V1a, V1b, V2) binding affinity, selectivity, and signal transduction pathways.
  • Drug Discovery & Development: Serves as a lead compound or intermediate in the design and synthesis of novel vasopressin receptor agonists or antagonists for potential therapeutic use.
  • Biochemical Assays: Used in in vitro and cell-based assays to study the physiological roles of vasopressin in water retention, blood pressure regulation, and social behavior.
  • Academic Studies: Fundamental research into peptide hormone structure, function, and metabolism within university and institutional laboratory settings.
  • Analytical Standard: Employed as a high-purity standard for method development and validation in analytical techniques like HPLC and LC-MS for peptide quantification.

Basic Information

Product Name Vasopressin, 2-Gly-9-Des-Gly-4-Val-8-Orn-
CAS No. 113846-98-3
Molecular Formula C45H68N14O12S2
Molecular Weight 1045.2 g/mol
Synonyms [2-Glycine, 9-De-Glycine, 4-Valine, 8-Ornithine]Vasopressin; [Gly², des-Gly⁹, Val⁴, Orn⁸]Vasopressin; Vasopressin (2-Gly-9-des-Gly-4-Val-8-Orn-); Ornithine Vasopressin Analog; 8-Orn-Vasopressin Fragment; AVP Analogue; (2-Gly,9-Des-Gly,4-Val,8-Orn)-Vasopressin
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Quality Control

Our Vasopressin analogue is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (HPLC) Retention time corresponds to reference standard
Identification (MS) Mass spectrum consistent with molecular formula
Purity (HPLC) ≥ 95.0%
Assay (Peptide Content) ≥ 80.0%
Water Content (KF) ≤ 5.0%
Acetate Content (HPLC) ≤ 10.0%
Single Impurity (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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